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The escalation of dosing regimens has resulted in a clearly evident, but not evolutionary increase in the muscle mass of the competitors. This is not true at similar intensity levels. The main purpose of this study was to understand whether the results observed in elite sportspersons were the consequence of either higher rates of recovery (e.g., higher glycogen stores) after exercise (25), more intense activity (e.g., higher volume) or some combination of these factors. The data, which comprise two crossover studies, indicate that the muscle mass in elite male athletes is increasing at a much higher rates than previously supposed. The mean gains in muscle mass in elite male athletes have been shown to be between 3 and 7g/kg (7). However, these results are often attributed to a higher relative recovery rate in the last few weeks between the competition and the training trial, a higher peak rate of muscle fibre adaptation (1, 2), increased muscle hypertrophy (1) or greater absolute training volume (1) than previously believed. We investigated the relation between muscle mass and the absolute volume in elite athletes to examine such factors. Our purpose was to examine whether the muscle mass achieved in competitive sport, as recorded by the measurement of muscle cross-sectional area (CSA) after resistance training and measured using the maximal isometric contraction (MIC) was related to the absolute training volume, as measured by the measurement of muscle cross-sectional area (CSA) with the same type of apparatus for one bout of maximal isometric contraction using the same stimuli (25). We also investigated whether the muscle mass gains achieved in elite males could be attributed to a combination of these factors. Materials and Methods Procedures All the studies were approved by the research ethics committee of the Centre National de la Recherche Scientifique (CNRS) (No. 805-0006) and written consent was obtained from each participant. The protocol was approved by the research ethics committee of the University Hospital Clinic (No. 100-010) and signed by the participating subjects. In this study, seven male volunteers (age 18–35 yr, range 21–49 yr; body mass 62 kg, 73.2 ± 7.6 kg) participated in the studies. The experimental procedure was identical to those used in the previous studies. The experimental protocol was registered with the European Central Registry for Clinical Studies (European Central Registry of Clinical Studies). The protocol number of the studies is published in table S1 and study number in table S2. Muscle preparation during the muscle strength test All the subjects Similar articles: